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Article

Genetic variants in the 3' untranslated region of sFRP1 gene and risk of gastric cancer in a Chinese population.

The International journal of biological markers - 2 Mar 2017

Wu Juan, Zhang Junfeng, Cao Qinhong, Wang Junqin, Zhan Zhen, Li Zhong

Abstract excerpt

BACKGROUND: Secreted frizzled-related protein 1 (sFRP1), a negative regulator of the Wnt signaling pathway, is frequently inactivated in human gastric cancer. Genetic variants in the 3' untranslated region (UTR) of the gene may influence the strength of miRNA binding and the regulation of mRNA transcription, affecting the individual's cancer risk. This study aims to investigate the impact of variants in the 3'...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27739564
DOI: 10.5301/jbm.5000233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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