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Article

Genetic Variants in the Wnt/β-Catenin Signaling Pathway as Indicators of Bladder Cancer Risk.

The Journal of urology - 1 Dec 2015

Pierzynski Jeanne A, Hildebrandt Michelle A, Kamat Ashish M, Lin Jie, Ye Yuanqing, Dinney Colin P N, Wu Xifeng

Abstract excerpt

PURPOSE: Genetic factors that influence bladder cancer risk remain largely unknown. Previous research has suggested that there is a strong genetic component underlying the risk of bladder cancer. The Wnt/β-catenin signaling pathway is a key modulator of cellular proliferation through its regulation of stem cell homeostasis. Furthermore, variants in the Wnt/β-catenin signaling pathway have been implicated in the...

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Identifiers

PMID: 26173102
DOI: 10.1016/j.juro.2015.07.032
PMCID: PMC5087323

Genes

LRP6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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