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Article

Significant association between MTHFR C677T polymorphism and hepatocellular carcinoma risk: a meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2014

Sun Hongli, Han Bing, Zhai Hongpeng, Cheng Xinhua, Ma Kai

Abstract excerpt

Previous studies investigated the association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and hepatocellular carcinoma risk, but the impact of MTHFR C677T polymorphism on hepatocellular carcinoma was still unclear, owing to the obvious inconsistence from those studies....

Topics

Alleles
Carcinoma, Hepatocellular
Case-Control Studies
Genetic Association Studies
Genetic Predisposition to Disease
Genotype
Humans
Liver Neoplasms
Methylenetetrahydrofolate Reductase (NADPH2)
Odds Ratio
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Publication Bias

Risk

Source

Identifiers

PMID: 24132589
DOI: 10.1007/s13277-013-1023-5

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-24132589-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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