Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and the risk of primary hepatocellular carcinoma (HCC) in a Chinese population.

Cancer causes & control : CCC - 1 Aug 2007

Mu Li-Na, Cao Wei, Zhang Zuo-Feng, Cai Lin, Jiang Qing-Wu, You Nai-Chieh, Goldstein Binh Yang, Wei Guo-Rong, Chen Chuan-Wei, Lu Qing-Yi, Zhou Xue-Fu, Ding Bao-Guo, Chang Jun, Yu Shun-Zhang

Abstract excerpt

OBJECTIVES: Methylenetetrahydrofolate reductase (MTHFR), which is expressed in the liver, may be involved in both DNA methylation and DNA synthesis. It is also indicated as a potential risk factor of liver cancer in patients with chronic liver disease. To date, no study has been conducted on MTHFR and hepatocellular carcinoma (HCC) using a population-based design. The objective of this study was to evaluate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Liver Neoplasms

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 17503006
DOI: 10.1007/s10552-007-9012-x
PMCID: PMC4165489

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and the risk of primary hepatocellular carcinoma (HCC) in a Chinese population.PMID 17503006Read ↗

Associations between methylenetetrahydrofolate reductase polymorphisms and hepatocellular carcinoma risk in Chinese population.Semantic proximity Read ↗

Significant association between MTHFR C677T polymorphism and hepatocellular carcinoma risk: a meta-analysis.Semantic proximity Read ↗

Folate metabolism-related gene polymorphisms and susceptibility to primary liver cancer in North China.Semantic proximity Read ↗

Associations of Methylenetetrahydrofolate reductase (MTHFR) polymorphism with Hepatocellular carcinoma In Egyptian population.Semantic proximity Read ↗

The association between MTHFR gene polymorphisms and hepatocellular carcinoma risk: a meta-analysis.Semantic proximity Read ↗

Genetic Polymorphism of MTHFR C677T Influences Susceptibility to HBV-Related Hepatocellular Carcinoma in a Chinese Population: a Case-Control Study.Semantic proximity Read ↗

Meta-analysis of MTHFR C677T and A1298C gene polymorphisms: association with the risk of hepatocellular carcinoma.Semantic proximity Read ↗

Significant association between the MTHFR A1298C polymorphism and hepatocellular carcinoma risk: a meta-analysis.Semantic proximity Read ↗

[A study on the association of MTHFR C677T polymorphism with genetic susceptibility to hepatocellular carcinoma].Semantic proximity Read ↗

Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) gene polymorphisms as risk factors for hepatocellular carcinoma in a Korean population.Semantic proximity Read ↗

Association between methylenetetrahydrofolate reductase tagging polymorphisms and susceptibility of hepatocellular carcinoma: a case-control study.Semantic proximity Read ↗

Association of GST genetic polymorphisms with the susceptibility to hepatocellular carcinoma (HCC) in Chinese population evaluated by an updated systematic meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.