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Article

Significant association between the MTHFR A1298C polymorphism and hepatocellular carcinoma risk: a meta-analysis.

Genetics and molecular research : GMR - 7 Dec 2015

Chang W, Meng Q, Liu J H, Wu L X, Chen Y, Chen S D

Abstract excerpt

The A1298C polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene has been reported to be associated with hepatocellular carcinoma (HCC), but there are conflicting results from previous studies. The present study aimed to investigate the association between this polymorphism and the risk of HCC using a meta-analysis of the published studies. Published literature from PubMed and Embase databases was...

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Source

Identifiers

PMID: 26662389
DOI: 10.4238/2015.December.7.9

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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