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Article

The association between MTHFR gene polymorphisms and hepatocellular carcinoma risk: a meta-analysis.

PloS one - 1 Jan 2013

Qin Xue, Peng Qiliu, Chen Zhiping, Deng Yan, Huang Shan, Xu Juanjuan, Li Haiwei, Li Shan, Zhao Jinmin

Abstract excerpt

BACKGROUND: The association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and hepatocellular carcinoma (HCC) risk was inconsistent and underpowered. To clarify the effects of MTHFR gene polymorphisms on the risk of HCC, a meta-analysis of all available studies relating C677T and/or A1298C polymorphisms of MTHFR gene to the risk of HCC was conducted. METHODS: The authors searched PubMed,...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Liver Neoplasms

Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Share to Polymorphism, Single Nucleotide

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Source

Open in PubMed Open full text

Identifiers

PMID: 23457501
DOI: 10.1371/journal.pone.0056070
PMCID: PMC3573065

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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