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Article

Ocular phenotype of Fbn2-null mice.

Investigative ophthalmology & visual science - 1 Nov 2013

Shi Yanrong, Tu Yidong, Mecham Robert P, Bassnett Steven

Abstract excerpt

PURPOSE: Fibrillin-2 (Fbn2) is the dominant fibrillin isoform expressed during development of the mouse eye. To test its role in morphogenesis, we examined the ocular phenotype of Fbn2(-/-) mice. METHODS: Ocular morphology was assessed by confocal microscopy using antibodies against microfibril components. RESULTS: Fbn2(-/-) mice had a high incidence of anterior segment dysgenesis. The iris was the most commonly...

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Identifiers

PMID: 24130178
DOI: 10.1167/iovs.13-12687
PMCID: PMC3816615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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