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Human Eye Development Is Characterized by Coordinated Expression of Fibrillin Isoforms

18 Nov 2014

Abstract excerpt

PURPOSE: Mutations in human fibrillin-1 and -2, which are major constituents of tissue microfibrils, can affect multiple ocular components, including the ciliary zonule, lens, drainage apparatus, cornea, and retina. However, the expression pattern of the three human fibrillins and an integral microfibrillar component, MAGP1, during human eye development is not known. METHODS: We analyzed sections from human eyes...

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PMID: 25406291
DOI: 10.1167/iovs.14-15453

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