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Article

Latent TGF-β binding protein-2 is essential for the development of ciliary zonule microfibrils.

Human molecular genetics - 1 Nov 2014

Inoue Tadashi, Ohbayashi Tetsuya, Fujikawa Yusuke, Yoshida Hideyuki, Akama Tomoya O, Noda Kazuo, Horiguchi Masahito, Kameyama Katsuro, Hata Yoshio, Takahashi Kanji, Kusumoto Kenji, Nakamura Tomoyuki

Abstract excerpt

Latent TGF-β-binding protein-2 (LTBP-2) is an extracellular matrix protein associated with microfibrils. Homozygous mutations in LTBP2 have been found in humans with genetic eye diseases such as congenital glaucoma and microspherophakia, indicating a critical role of the protein in eye developmen...

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Identifiers

PMID: 24908666
DOI: 10.1093/hmg/ddu283
PMCID: PMC4189902

Genes

LTBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24908666-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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