Article
Reduced burden of very large and rare CNVs in bipolar affective disorder.
Bipolar disorders - 1 Dec 2013
Grozeva Detelina, Kirov George, Conrad Donald F, Barnes Chris P, Hurles Matthew, Owen Michael J, O'Donovan Michael C, Craddock Nick
Abstract excerpt
OBJECTIVES: Large, rare chromosomal copy number variants (CNVs) have been shown to increase the risk for schizophrenia and other neuropsychiatric disorders including autism, attention-deficit hyperactivity disorder, learning difficulties, and epilepsy. Their role in bipolar disorder (BD) is less clear. There are no reports of an increase in large, rare CNVs in BD in general, but some have reported an increase in...
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