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Article

Genomic landscape of a three-generation pedigree segregating affective disorder.

PloS one - 1 Jan 2009

Yang Shuzhang, Wang Kai, Gregory Brittany, Berrettini Wade, Wang Li-San, Hakonarson Hakon, Bucan Maja

Abstract excerpt

Bipolar disorder (BPD) is a common psychiatric illness with a complex mode of inheritance. Besides traditional linkage and association studies, which require large sample sizes, analysis of common and rare chromosomal copy number variants (CNVs) in extended families may provide novel insights into the genetic susceptibility of complex disorders. Using the Illumina HumanHap550 BeadChip with over 550,000 SNP...

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Identifiers

PMID: 19214233
DOI: 10.1371/journal.pone.0004474
PMCID: PMC2637422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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