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Article

De novo CNVs in bipolar affective disorder and schizophrenia.

Human molecular genetics - 15 Dec 2014

Georgieva Lyudmila, Rees Elliott, Moran Jennifer L, Chambert Kimberly D, Milanova Vihra, Craddock Nicholas, Purcell Shaun, Sklar Pamela, McCarroll Steven, Holmans Peter, O'Donovan Michael C, Owen Michael J, Kirov George

Abstract excerpt

An increased rate of de novo copy number variants (CNVs) has been found in schizophrenia (SZ), autism and developmental delay. An increased rate has also been reported in bipolar affective disorder (BD). Here, in a larger BD sample, we aimed to replicate these findings and compare de novo CNVs between SZ and BD. We used Illumina microarrays to genotype 368 BD probands, 76 SZ probands and all their parents. Copy...

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Identifiers

PMID: 25055870
DOI: 10.1093/hmg/ddu379
PMCID: PMC4240207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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