Article
Structural and functional characterization of the MERIT40 to understand its role in DNA repair.
Journal of biomolecular structure & dynamics - 1 Dec 2014
Vikrant, Nakhwa Pallavi, Badgujar Dilip C, Kumar Rajan, Rathore Khushboo K S, Varma Ashok K
Abstract excerpt
MERIT40 (MEdiator of RAP80 Interaction and Targeting 40) is a novel associate of the BRCA1-complex and plays an essential role in DNA damage repair. It is the least characterized protein of BRCA1-complex and mainly responsible for maintaining the complex integrity. However, its structural and functional aspects of regulating the complex stability still remain elusive. Here, we carried out a comprehensive...
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