Article
Exome array analysis of ischaemic stroke: results from a southern Swedish study.
European journal of neurology - 1 Dec 2016
Söderholm M, Almgren P, Jood K, Stanne T M, Olsson M, Ilinca A, Lorentzen E, Norrving B, Engström G, Melander O, Jern C, Lindgren A
Abstract excerpt
BACKGROUND AND PURPOSE: Genome-wide association (GWA) studies have identified a few risk loci for ischaemic stroke, but these variants explain only a small part of the genetic contribution to the disease. Coding variants associated with amino acid substitutions or premature termination of protein synthesis could have a large effect on disease risk. We performed an exome array analysis for ischaemic stroke....
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