Article
Association between two key SNPs on chromosome 12p13 and ischemic stroke in Chinese Han population.
Pharmacogenetics and genomics - 1 Sept 2011
Tong Yeqing, Zhang Yanwei, Zhang Renli, Geng Yijie, Lin Liangqiang, Wang Zhihong, Liu Jianping, Li Xiaoxia, Cao Zhixin, Xu Jing, Chai Yun, Fan Hong, Hu Frank B, Lu Zuxun, Cheng Jinquan
Abstract excerpt
OBJECTIVE: Genome-wide single nucleotide polymorphism (SNP) association studies recently identified two SNPs (rs11833579 and rs12425791) on chromosome 12p13 that are associated with ischemic stroke (IS) in Caucasian or Black persons from America and the Netherlands. Our aim was to determine whether these SNPs were associated with IS in Chinese Han population. METHODS: We used a case-control study involving 648 IS...
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