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Article

Targeted disruption of an EH-domain protein endocytic complex, Pan1-End3.

Traffic (Copenhagen, Denmark) - 1 Jan 2014

Whitworth Karen, Bradford Mary Katherine, Camara Nicole, Wendland Beverly

Abstract excerpt

Pan1 is a multi-domain scaffold that enables dynamic interactions with both structural and regulatory components of the endocytic pathway. Pan1 is composed of Eps15 Homology (EH) domains which interact with adaptor proteins, a central region that is responsible for its oligomerization and C-terminal binding sites for Arp2/3, F-actin, and type-I myosin motors. In this study, we have characterized the binding sites...

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Identifiers

PMID: 24118836
DOI: 10.1111/tra.12125
PMCID: PMC3855908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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