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Article

Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis.

The Journal of cell biology - 6 Apr 1998

Wendland B, Emr S D

Abstract excerpt

A genetic screen for factors required for endocytosis in the budding yeast Saccharomyces cerevisiae previously identified PAN1. Pan1p is a homologue of the mammalian protein eps15, which has been implicated in endocytosis by virtue of its association with the plasma membrane clathrin adaptor complex AP-2. Pan1p contains two eps15 homology (EH) domains, a protein-protein interaction motif also present in other...

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Identifiers

PMID: 9531549
DOI: 10.1083/jcb.141.1.71
PMCID: PMC2132731

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Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis.PMID 9531549Read ↗

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