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Article

Discriminant analysis of prion sequences for prediction of susceptibility.

Experimental & molecular medicine - 11 Oct 2013

Lee Ji-Hae, Bae Se-Eun, Jung Sunghoon, Ahn Insung, Son Hyeon Seok

Abstract excerpt

Prion diseases, including ovine scrapie, bovine spongiform encephalopathy (BSE), human kuru and Creutzfeldt-Jakob disease (CJD), originate from a conformational change of the normal cellular prion protein (PrP(C)) into abnormal protease-resistant prion protein (PrP(Sc)). There is concern regarding these prion diseases because of the possibility of their zoonotic infections across species. Mutations and...

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Source

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Identifiers

PMID: 24113272
DOI: 10.1038/emm.2013.100
PMCID: PMC3809358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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