Article
DNA polymorphisms of the prion doppel gene region in four different German cattle breeds and cows tested positive for bovine spongiform encephalopathy.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Nov 2005
Balbus N, Humeny A, Kashkevich K, Henz I, Fischer C, Becker C-M, Schiebel K
Abstract excerpt
Polymorphisms of the prion protein gene PRNP have been shown to influence the susceptibility/resistance to prion infections in human and sheep. In addition, the T174M polymorphism within the flanking prion doppel gene (PRND) was thought to be involved in susceptibility to sporadic Creutzfeldt-Jacob disease. To study a possible influence of DNA polymorphisms of the bovine PRND gene in bovine spongiform...
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