Article
A new genotyping strategy for efficient scoring of closely positioned SNPs in the ovine prion protein gene.
Molecular and cellular probes - 1 Apr 2009
Pongolini Stefano, Bergamini Federica, Bassi Stefano
Abstract excerpt
Amino-acid polymorphisms of the ovine prion protein have been known to influence susceptibility to scrapie for many years. Recently, a role in both classical and atypical scrapie was assigned to new mutations, increasing the overall number of polymorphisms of interest for breeding plans. Besides, the high number and density of polymorphisms in the prion protein gene (PrP) and the presence of unusual mutations in...
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