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Article

Prion's progress: patterns and rates of molecular evolution in relation to spongiform disease.

Journal of molecular evolution - 1 Aug 1998

Krakauer D C, Zanotto P M, Pagel M

Abstract excerpt

Modification of the cellular prion protein has been correlated with the acquisition of several neurodegenerative diseases, including kuru, scrapie, bovine spongiform encephalopathy (BSE), and Creutzfeldt-Jakob disease (CJD). Sequence conservation and amino acid identity are known to influence the efficacy of interspecific transmission. We analyzed patterns of interspecific genetic variation with a view toward...

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Identifiers

PMID: 9694662
DOI: 10.1007/pl00006370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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