Article
Genetics of transmissible spongiform encephalopathy susceptibility and the search for surrogate markers for infection.
2004-01-01
Abstract excerpt
The transmissible spongiform encephalopathy diseases are unusual in that they can be sporadic or infectious, and that the infectious agent does not contain nucleic acids. Instead, infectivity is associated with a modified host-encoded protein referred to as a prion. During the course of disease, host encoded prion protein (PrP) is converted from the normal cellular form, PrP<sup>C</sup>, to a disease form, PrP<sup...
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Identifiers and source
- Literature Corpus work
- 9423ab03-1d69-543b-ab53-6a371d0a8944
- DOI
- 10.1071/ea03235
