Article
BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease.
Science translational medicine - 9 Oct 2013
Shum Anthony K, Alimohammadi Mohammad, Tan Catherine L, Cheng Mickie H, Metzger Todd C, Law Christopher S, Lwin Wint, Perheentupa Jaakko, Bour-Jordan Helene, Carel Jean Claude, Husebye Eystein S, De Luca Filippo, Janson Christer, Sargur Ravishankar, Dubois Noémie, Kajosaari Merja, Wolters Paul J, Chapman Harold A, Kämpe Olle, Anderson Mark S
Abstract excerpt
Interstitial lung disease (ILD) is a complex and heterogeneous disorder that is often associated with autoimmune syndromes. Despite the connection between ILD and autoimmunity, it remains unclear whether ILD can develop from an autoimmune response that specifically targets the lung parenchyma. We examined a severe form of autoimmune disease, autoimmune polyglandular syndrome type 1 (APS1), and established a...
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