Article

Validation of a murine proteome-wide phage display library for the identification of autoantibody specificities

2023-04-07

Abstract excerpt

<h4>ABSTRACT</h4> Autoimmunity is characterized by loss of tolerance to tissue-specific as well as systemic antigens, resulting in complex autoantibody landscapes. Here, we introduce and extensively validate the performance characteristics of a murine proteome-wide library for phage display immunoprecipitation and sequencing (PhIP-seq), to profile mouse autoantibodies. This system and library were validated using...

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Literature Corpus work: 841aa29a-630b-5046-ab5d-613e215edd01
DOI: 10.1101/2023.04.07.535899

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