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Article

AHR and NRF2 in Skin Homeostasis and Atopic Dermatitis

25 Jan 2022

Abstract excerpt

Skin is constantly exposed to environmental insults, including toxic chemicals and oxidative stress. These insults often provoke perturbation of epidermal homeostasis and lead to characteristic skin diseases. AHR (aryl hydrocarbon receptor) and NRF2 (nuclear factor erythroid 2-related factor 2) are transcription factors that induce a battery of cytoprotective genes encoding detoxication and antioxidant enzymes in...

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Identifiers

PMID: 35204110
DOI: 10.3390/antiox11020227

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