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Article

Genetic variations and haplotype structures of transcriptional factor Nrf2 and its cytosolic reservoir protein Keap1 in Japanese.

Drug metabolism and pharmacokinetics - 1 Jun 2007

Fukushima-Uesaka Hiromi, Saito Yoshiro, Maekawa Keiko, Kamatani Naoyuki, Kajio Hiroshi, Kuzuya Nobuaki, Noda Mitsuhiko, Yasuda Kazuki, Sawada Jun-ichi

Abstract excerpt

Transcriptional factor Nrf2 and its cytosolic reservoir protein Keap1 play important roles in induction of the expression of genes for xenobiotic metabolism and disposition, many of which are involved in protection from oxidative stress. In this study, 5 NFE2L2 (encoding Nrf2) and 6 KEAP1 exons and their flanking introns were comprehensively screened for genetic variations in 84 Japanese subjects. As for NFE2L2,...

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Identifiers

PMID: 17603223
DOI: 10.2133/dmpk.22.212

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KEAP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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