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Article

Microvesicle- and exosome-mediated drug delivery enhances the cytotoxicity of Paclitaxel in autologous prostate cancer cells.

Journal of controlled release : official journal of the Controlled Release Society - 28 Dec 2015

Saari Heikki, Lázaro-Ibáñez Elisa, Viitala Tapani, Vuorimaa-Laukkanen Elina, Siljander Pia, Yliperttula Marjo

Abstract excerpt

BACKGROUND: Extracellular vesicles (EVs) are naturally occurring membrane particles that mediate intercellular communication by delivering molecular information between cells. In this study, we investigated the effectiveness of two different populations of EVs (microvesicle- and exosome-enriched) as carriers of Paclitaxel to autologous prostate cancer cells. METHODS: EVs were isolated from LNCaP- and PC-3...

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Identifiers

PMID: 26390807
DOI: 10.1016/j.jconrel.2015.09.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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