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Article

Kinesin Facilitates Phenotypic Targeting of Therapeutic Resistance in Advanced Prostate Cancer.

Molecular cancer research : MCR - 2 Aug 2024

Archer Maddison, Begemann Diane, Gonzalez-Kozlova Edgar, Nepali Prerna R, Labanca Estefania, Shepherd Peter, Dogra Navneet, Navone Nora, Kyprianou Natasha

Abstract excerpt

Understanding the mechanisms underlying resistance is critical to improving therapeutic outcomes in patients with metastatic castration-resistant prostate cancer. Previous work showed that dynamic interconversions between epithelial-mesenchymal transition to mesenchymal-epithelial transition defines the phenotypic landscape of prostate tumors, as a potential driver of the emergence of therapeutic resistance. In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38648082
DOI: 10.1158/1541-7786.MCR-23-1047
PMCID: PMC11296928

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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