Article
An original patient-derived xenograft of prostate cancer with cyst formation.
The Prostate - 1 Aug 2016
Yoshikawa Takeshi, Kobori Go, Goto Takayuki, Akamatsu Shusuke, Terada Naoki, Kobayashi Takashi, Tanaka Yoshinori, Jung Giman, Kamba Tomomi, Ogawa Osamu, Inoue Takahiro
Abstract excerpt
BACKGROUND: The high rate of failure of new agents in oncology clinical trials indicates a weak understanding of the complexity of human cancer. Recent understanding of the mechanisms underlying castration resistance in prostate cancer led to the development of new agents targeting the androgen receptor pathway; however, their effectiveness is limited. Hence, there is a need for experimental systems that are able...
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