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Article

Resection activity of the Sgs1 helicase alters the affinity of DNA ends for homologous recombination proteins in Saccharomyces cerevisiae.

Genetics - 1 Dec 2013

Bernstein Kara A, Mimitou Eleni P, Mihalevic Michael J, Chen Huan, Sunjaveric Ivana, Symington Lorraine S, Rothstein Rodney

Abstract excerpt

The RecQ helicase family is critical during DNA damage repair, and mutations in these proteins are associated with Bloom, Werner, or Rothmund-Thompson syndromes in humans, leading to cancer predisposition and/or premature aging. In the budding yeast Saccharomyces cerevisiae, mutations in the RecQ...

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Identifiers

PMID: 24097410
DOI: 10.1534/genetics.113.157370
PMCID: PMC3832270

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24097410-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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