Article
Association of IL-17A and IL-17F single nucleotide polymorphisms with susceptibility to osteoarthritis in a Korean population.
Gene - 1 Jan 2014
Han Lin, Lee Hwa Sung, Yoon Jung Hwan, Choi Won Suk, Park Yong Gyu, Nam Suk Woo, Lee Jung Young, Park Won Sang
Abstract excerpt
The damage incurred in osteoarthritis (OA) is mediated by a variety of cytokines, growth factors and inflammatory mediators. The importance of the interleukin-17 (IL-17) family in inflammatory and autoimmune disease is becoming increasingly apparent. Microsatellite association mapping reveals a p...
Topics
- Base Sequence
- DNA Primers
- Female
- Genetic Predisposition to Disease
- Humans
- Interleukin-17
- Male
- Middle Aged
- Osteoarthritis
- Polymerase Chain Reaction
- Polymorphism, Single Nucleotide
- Republic of Korea