Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in the prediction of rheumatoid arthritis.

Annals of the rheumatic diseases - 1 Sept 2010

van der Helm-van Mil Annette H M, Toes René E M, Huizinga Tom W J

Abstract excerpt

OBJECTIVE: To determine whether the currently known genetic risk factors for rheumatoid arthritis (RA) improve the prediction of the development of RA compared to prediction using clinical risk factors alone in patients with undifferentiated arthritis (UA). METHODS: Five hundred and seventy early UA-patients included in the Leiden Early Arthritis Clinic cohort, previously used to derive a clinical prediction...

Topics

Join the communities discussing this publication.

TRAF1 gene
Epidemiologic Methods
Disease Progression
Arthritis, Rheumatoid
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-DR Antigens

HLA-DRB1 Chains

Source

Identifiers

PMID: 20439292
DOI: 10.1136/ard.2009.123828

Genes

PTPN22
CCL21
CDK6
CTLA4
MMEL1
OLIG3
PRKCQ
STAT4
TNFAIP3
TNFRSF14
TRAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in the prediction of rheumatoid arthritis.PMID 20439292Read ↗

A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk.Semantic proximity Read ↗

A genetic risk score composed of rheumatoid arthritis risk alleles, HLA-DRB1 haplotypes, and response to TNFi therapy - results from a Swedish cohort study.Semantic proximity Read ↗

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis.Semantic proximity Read ↗

Pulmonary fibrosis in relation to genetic loci in an inception cohort of patients with early rheumatoid arthritis from northern Sweden.Semantic proximity Read ↗

Role of Selected Genetic Polymorphisms in the Development of Rheumatoid Arthritis in a British White Population.Semantic proximity Read ↗

Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers.Semantic proximity Read ↗

Comparison of methods to construct a genetic risk score for prediction of rheumatoid arthritis in the population-based Nord-Trøndelag Health Study, Norway.Semantic proximity Read ↗

The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register.Semantic proximity Read ↗

Machine learning-based prediction of rheumatoid arthritis with development of ACPA autoantibodies in the presence of non-HLA genes polymorphisms.Semantic proximity Read ↗

Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci.Semantic proximity Read ↗

Using Polygenic Risk Scores to Aid Diagnosis of Patients With Early Inflammatory Arthritis: Results From the Norfolk Arthritis Register.Semantic proximity Read ↗

Low-frequency and rare genetic variants associated with rheumatoid arthritis risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.