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Litter Size Reduction as a Model of Overfeeding during Lactation and Its Consequences for the Development of Metabolic Diseases in the Offspring

13 May 2022

Abstract excerpt

Overfeeding during lactation has a deleterious impact on the baby's health throughout life. In humans, early overnutrition has been associated with higher susceptibility to obesity and metabolic disorders in childhood and adulthood. In rodents, using a rodent litter size reduction model (small litter) to mimic early overfeeding, the same metabolic profile has been described. Therefore, the rodent small litter...

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PMID: 35631188
DOI: 10.3390/nu14102045

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