Article
Analysis of the VAV3 as candidate gene for schizophrenia: evidences from voxel-based morphometry and mutation screening.
Schizophrenia bulletin - 1 May 2013
Aleksic Branko, Kushima Itaru, Hashimoto Ryota, Ohi Kazutaka, Ikeda Masashi, Yoshimi Akira, Nakamura Yukako, Ito Yoshihito, Okochi Tomo, Fukuo Yasuhisa, Yasuda Yuka, Fukumoto Motoyuki, Yamamori Hidenaga, Ujike Hiroshi, Suzuki Michio, Inada Toshiya, Takeda Masatoshi, Kaibuchi Kozo, Iwata Nakao, Ozaki Norio
Abstract excerpt
In recently completed Japanese genome-wide association studies (GWAS) of schizophrenia (JPN_GWAS) one of the top association signals was detected in the region of VAV3, a gene that maps to the chromosome 1p13.3. In order to complement JPN_GWAS findings, we tested the association of rs1410403 with brain structure in healthy individuals and schizophrenic patients and performed exon resequencing of VAV3. We...
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