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Article

Familial and environmental influences on brain volumes in twins with schizophrenia.

Journal of psychiatry & neuroscience : JPN - 1 Mar 2017

Picchioni Marco M, Rijsdijk Fruhling, Toulopoulou Timothea, Chaddock Christopher, Cole James H, Ettinger Ulrich, Oses Ana, Metcalfe Hugo, Murray Robin M, McGuire Philip

Abstract excerpt

BACKGROUND: Reductions in whole brain and grey matter volumes are robust features of schizophrenia, yet their etiological influences are unclear. METHODS: We investigated the association between the genetic and environmental risk for schizophrenia and brain volumes. Whole brain, grey matter and white matter volumes were established from structural MRIs from twins varying in their zygosity and concordance for...

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Identifiers

PMID: 28245176
DOI: 10.1503/jpn.140277
PMCID: PMC5373701

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