Article
Dysfunctional brain networks and genetic risk for schizophrenia: specific neurotransmitter systems.
CNS neuroscience & therapeutics - 1 Apr 2011
Hirvonen Jussi, Hietala Jarmo
Abstract excerpt
Multiple neurotransmitter circuits are disturbed in schizophrenia, and the dopamine hypothesis of schizophrenia prevails as the hypothesis with most empirical support. On the other hand, schizophrenia is highly heritable with a pattern consistent with both common and rare allelic variants and gene × environment interaction. Advances in the field of neuroimaging have expanded our knowledge of intermediate...
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