Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 2013

Wang Jiping, Carvajal-Carmona Luis G, Chu Jen-Hwa, Zauber Ann G, Kubo Michikai, Matsuda Koichi, Dunlop Malcolm, Houlston Richard S, Sieber Oliver, Lipton Lara, Gibbs Peter, Martin Nicholas G, Montgomery Grant W, Young Joanne, Baird Paul N, Ratain Mark J, Nakamura Yusuke, Weiss Scott T, Tomlinson Ian, Bertagnolli Monica M

Abstract excerpt

PURPOSE: Identification of single-nucleotide polymorphisms (SNP) associated with development of advanced colorectal adenomas. EXPERIMENTAL DESIGN: Discovery phase: 1,406 Caucasian patients (139 advanced adenoma cases and 1,267 controls) from the Adenoma Prevention with Celecoxib (APC) trial were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma
Share to Anticarcinogenic Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene-Environment Interaction

Share to Germ-Line Mutation

Share to Neoplasm Recurrence, Local

Share to Pyrazoles

Share to Randomized Controlled Trials as Topic

Share to Sulfonamides

Source

Open in PubMed Open full text

Identifiers

PMID: 24084763
DOI: 10.1158/1078-0432.CCR-13-0550
PMCID: PMC4037290

Genes

APC
IGSF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24084763-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.PMID 24084763Read ↗

Impact of genetic polymorphisms on adenoma recurrence and toxicity in a COX2 inhibitor (celecoxib) trial: results from a pilot study.Semantic proximity Read ↗

Cyclooxygenase-2 polymorphisms, aspirin treatment, and risk for colorectal adenoma recurrence--data from a randomized clinical trial.Semantic proximity Read ↗

Genome-wide association study identifies possible genetic risk factors for colorectal adenomas.Semantic proximity Read ↗

Innate immunity gene polymorphisms and the risk of colorectal neoplasia.Semantic proximity Read ↗

Variants downstream of the ornithine decarboxylase gene influence risk of colorectal adenoma and aspirin chemoprevention.Semantic proximity Read ↗

Polymorphisms in the adenomatous polyposis coli (APC) gene and advanced colorectal adenoma risk.Semantic proximity Read ↗

Ornithine decarboxylase G316A genotype is prognostic for colorectal adenoma recurrence and predicts efficacy of aspirin chemoprevention.Semantic proximity Read ↗

The influence of UGT1A6 variants and aspirin use in a randomized trial of celecoxib for prevention of colorectal adenoma.Semantic proximity Read ↗

Genetic Variants Associated with Colorectal Adenoma Susceptibility.Semantic proximity Read ↗

Nucleotide excision repair gene polymorphisms and risk of advanced colorectal adenoma: XPC polymorphisms modify smoking-related risk.Semantic proximity Read ↗

Variation in the association between colorectal cancer susceptibility loci and colorectal polyps by polyp type.Semantic proximity Read ↗

Transforming growth factor beta 1 (TGFB1) gene polymorphisms and risk of advanced colorectal adenoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.