Article
Innate immunity gene polymorphisms and the risk of colorectal neoplasia.
Carcinogenesis - 1 Nov 2013
Chang Cindy M, Chia Victoria M, Gunter Marc J, Zanetti Krista A, Ryan Bríd M, Goodman Julie E, Harris Curtis C, Weissfeld Joel, Huang Wen-Yi, Chanock Stephen, Yeager Meredith, Hayes Richard B, Berndt Sonja I
Abstract excerpt
Inherited variation in genes that regulate innate immunity and inflammation may contribute to colorectal neoplasia risk. To evaluate this association, we conducted a nested case-control study of 451 colorectal cancer cases, 694 colorectal advanced adenoma cases and 696 controls of European descent within the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. A total of 935 tag single-nucleotide...
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