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Article

Genetic interactions within inositol-related pathways are associated with longitudinal changes in ventricle size.

Journal of Alzheimer's disease : JAD - 1 Jan 2014

Koran Mary Ellen I, Hohman Timothy J, Meda Shashwath A, Thornton-Wells Tricia A

Abstract excerpt

The genetic etiology of late-onset Alzheimer's disease (LOAD) has proven complex, involving clinical and genetic heterogeneity and gene-gene interactions. Recent genome wide association studies in LOAD have led to the discovery of novel genetic risk factors; however, the investigation of gene-gene interactions has been limited. Conventional genetic studies often use binary disease status as the primary phenotype,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24077433
DOI: 10.3233/JAD-130989
PMCID: PMC3815519

Genes

SYNJ2
MYH2
PARD3
PRKG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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