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Article

Common SCN10A variants modulate PR interval and heart rate response during atrial fibrillation.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology - 1 Apr 2014

Delaney Jessica T, Muhammad Raafia, Shi Yaping, Schildcrout Jonathan S, Blair Marcia, Short Laura, Roden Dan M, Darbar Dawood

Abstract excerpt

AIMS: SCN10A encodes the sodium channel Nav1.8 implicated by genome-wide association studies as a modulator of atrioventricular conduction (PR interval). In a cohort of patients with atrial fibrillation (AF), we examined whether there was an association between common variants in SCN10A and both the PR interval during normal sinus rhythm and the heart rate response during AF. METHODS AND RESULTS: Patients...

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Identifiers

PMID: 24072447
DOI: 10.1093/europace/eut278
PMCID: PMC3977588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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