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Article

Circulating TFH subset distribution is strongly affected in lupus patients with an active disease.

PloS one - 1 Jan 2013

Le Coz Carole, Joublin Aurélie, Pasquali Jean-Louis, Korganow Anne-Sophie, Dumortier Hélène, Monneaux Fanny

Abstract excerpt

Follicular helper T cells (TFH) represent a distinct subset of CD4(+) T cells specialized in providing help to B lymphocytes, which may play a central role in autoimmune diseases having a major B cell component such as systemic lupus erythematosus. Recently, TFH subsets that share common phenotypic and functional characteristics with TFH cells from germinal centers, have been described in the peripheral blood...

Read the complete abstract on PubMed

Topics

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Share to CD4 Lymphocyte Count
Share to CD5 Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin E

Share to Immunologic Memory

Share to Immunophenotyping

Share to Lupus Erythematosus, Systemic

Share to T-Lymphocytes, Helper-Inducer

Share to Th2 Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 24069401
DOI: 10.1371/journal.pone.0075319
PMCID: PMC3777901

Genes

CCR6
CXCR3
CXCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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