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Article

Aberrant populations of circulating T follicular helper cells and regulatory B cells underlying idiopathic pulmonary fibrosis.

Respiratory research - 6 Nov 2019

Asai Yuichiro, Chiba Hirofumi, Nishikiori Hirotaka, Kamekura Ryuta, Yabe Hayato, Kondo Shun, Miyajima Satsuki, Shigehara Katsunori, Ichimiya Shingo, Takahashi Hiroki

Abstract excerpt

BACKGROUND: T follicular helper (Tfh) cells have been identified as a new category of helper T cells, which express CXCR5 on their surface and induce the production of antigen-specific antibodies. Many investigations have found morbid proliferation and/or activation of Tfh cells in systemic autoimmune and allergic diseases. It is also known that Tfh cells are regulated by regulatory B (Breg) cells in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Immunity, Humoral

Share to Inducible T-Cell Co-Stimulator Protein

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Share to T-Lymphocytes, Helper-Inducer

Source

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Identifiers

PMID: 31694639
DOI: 10.1186/s12931-019-1216-6
PMCID: PMC6836348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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