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Increased frequency of CD4 <sup>+</sup> and CD8 <sup>+</sup> follicular helper T cells in human lymph node biopsies during the earliest stages of rheumatoid arthritis

2021-11-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Follicular helper T cells (Tfh cells) provide key B cell help, and are essential in germinal center (GC) formation and (auto) antibody generation. To gain more insight into their role during the earliest phase of rheumatoid arthritis (RA) we analyzed their frequencies, phenotype and cytokine profile in peripheral blood and lymphoid tissues. <h4>Methods</h4> Using flow cytom...

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Literature Corpus work
469d300f-791f-5a60-b9a8-097a2cfa64b1
DOI
10.1101/2021.11.10.467883
Open publication

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Increased frequency of CD4 <sup>+</sup> and CD8 <sup>+</sup> follicular helper T cells in human lymph node biopsies during the earliest stages of rheumatoid arthritisDOI 10.1101/2021.11.10.467883
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