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Article

The initiation of epigenetic silencing of active transposable elements is triggered by RDR6 and 21-22 nucleotide small interfering RNAs.

Plant physiology - 1 May 2013

Nuthikattu Saivageethi, McCue Andrea D, Panda Kaushik, Fultz Dalen, DeFraia Christopher, Thomas Erica N, Slotkin R Keith

Abstract excerpt

Transposable elements (TEs) are mobile fragments of DNA that are repressed in both plant and animal genomes through the epigenetic inheritance of repressed chromatin and expression states. The epigenetic silencing of TEs in plants is mediated by a process of RNA-directed DNA methylation (RdDM). Two pathways of RdDM have been identified: RNA Polymerase IV (Pol IV)-RdDM, which has been shown to be responsible for...

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Identifiers

PMID: 23542151
DOI: 10.1104/pp.113.216481
PMCID: PMC3641197

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