Article
The prefoldin complex regulates chromatin dynamics during transcription elongation.
PLoS genetics - 1 Jan 2013
Millán-Zambrano Gonzalo, Rodríguez-Gil Alfonso, Peñate Xenia, de Miguel-Jiménez Lola, Morillo-Huesca Macarena, Krogan Nevan, Chávez Sebastián
Abstract excerpt
Transcriptional elongation requires the concerted action of several factors that allow RNA polymerase II to advance through chromatin in a highly processive manner. In order to identify novel elongation factors, we performed systematic yeast genetic screening based on the GLAM (Gene Length-depend...
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