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Article

Tetherin/BST-2: Restriction Factor or Immunomodulator?

Current HIV research - 1 Jan 2016

Li Sam X, Barrett Bradley S, Guo Kejun, Santiago Mario L

Abstract excerpt

BACKGROUND: Cell-mediated immune (CMI) responses are critical for the control of HIV-1 infection and their importance was highlighted by the existence of viral proteins, particularly Vpu and Nef, that antagonize these responses. Pandemic HIV-1 Vpu counteracts Tetherin/BST-2, a host factor that could prevent the release of HIV-1 virions by tethering virions on the cell surface, but a link between Tetherin and...

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Identifiers

PMID: 26957198
DOI: 10.2174/1570162x14999160224102752
PMCID: PMC5466165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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