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Article

Study of hepatitis B virus gene mutations with enzymatic colorimetry-based DNA microarray.

Clinical biochemistry - 1 Jan 2006

Mao Hailei, Wang Huimin, Zhang Donglei, Mao Hongju, Zhao Jianlong, Shi Jian, Cui Zhichu

Abstract excerpt

OBJECTIVES: To establish a modified microarray method for detecting HBV gene mutations in the clinic. DESIGN AND METHODS: Site-specific oligonucleotide probes were immobilized to microarray slides and hybridized to biotin-labeled HBV gene fragments amplified from two-step PCR. Hybridized targets were transferred to nitrocellulose membranes, followed by intensity measurement using BCIP/NBT colorimetry. RESULTS:...

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Identifiers

PMID: 16330012
DOI: 10.1016/j.clinbiochem.2005.10.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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