Article
Development and clinical evaluation of a microarray for hepatitis C virus genotyping.
Journal of virological methods - 1 Feb 2010
Park Jae-Chan, Kim Jong-Man, Kwon Oh-Joong, Lee Kyoung-Ryul, Chai Young-Guy, Oh Heung-Bum
Abstract excerpt
The hepatitis C virus (HCV) genotype is the most important factor in predicting the outcome of chronic hepatitis C treatment. Therefore, convenient and accurate HCV genotyping methods for routine laboratory testing are needed. In this study, to identify the HCV genotypes, an oligonucleotide DNA chip was designed using 15 probes from the 5'-untranslated region. Reverse transcription was combined with asymmetric...
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