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Article

A type-specific nested PCR assay established and applied for investigation of HBV genotype and subgenotype in Chinese patients with chronic HBV infection.

Virology journal - 19 Jun 2012

Nie Jing-Jing, Sun Kui-Xia, Li Jie, Wang Jie, Jin Hui, Wang Ling, Lu Feng-Min, Li Tong, Yan Ling, Yang Jing-Xian, Sun Mi-Shu, Zhuang Hui

Abstract excerpt

BACKGROUND: Many studies have suggested that hepatitis B virus (HBV) genotypes show not only geographical distribution and race specificity, but also are associated with disease progression and response to interferon treatment. The objective of this study was to develop a nested polymerase chain reaction (nPCR) assay for genotypes A-D and subgenotypes B1, B2, C1 and C2 of hepatitis B virus (HBV) and to...

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Identifiers

PMID: 22716091
DOI: 10.1186/1743-422X-9-121
PMCID: PMC3477104

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