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Article

NRG3 gene is associated with the risk and age at onset of Alzheimer disease.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Feb 2014

Wang Ke-Sheng, Xu Nuo, Wang Liang, Aragon Lorenzo, Ciubuc Radu, Arana Tania Bedard, Mao Chunxiang, Petty Leonora, Briones David, Su Brenda Bin, Luo Xingguang, Camarillo Cynthia, Escamilla Michael A, Xu Chun

Abstract excerpt

The Neuregulin 3 (NRG3) gene at 10q22-q24 has been implicated in multiple psychiatric traits such as cognitive impairment. We therefore hypothesized that NRG3 gene polymorphisms may play a role in Alzheimer disease (AD). This present study explored the association of NRG3 with the age at onset (AAO) of AD and the risk of developing AD. Secondary data analysis of 257 single-nucleotide polymorphisms (SNPs) in NRG3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24061483
DOI: 10.1007/s00702-013-1091-0

Genes

NRG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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